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Objective@#The study was aimed at exploring the latent classes and factors influencing middle school students health risk behaviors in Beijing, so as to provide a scientific basis for determining key intervention targets and formulating relevant intervention measures.@*Methods@#A questionnaire survey was conducted among 17 730 junior middle school, senior high school and vocational high school students in 16 districts of Beijing from October to December 2022. Six types of health risk behaviors were assessed with latent class analysis, including unhealthy diet, lack of exercise, unintentional harm, intentional harm, substance abuse and Internet addiction behavior.@*Results@#The latent classes of health risk behavior among middle school students in Beijing were divided into three classes:high risk behavior (961 participants, 5.42%), low lack of exercise/high intentional injury (1 099 participants, 6.20%), and low risk behavior (15 670 participants, 88.38%). Disordered multiple Logistic regression analysis indicated that middle school students who were male ( OR =1.45), in high school ( OR =2.00), had other family types ( OR =1.90), possibly had depressed feelings ( OR =2.27), had depressed feelings ( OR =6.18), or were absent from school because of illness in the past year ( OR =1.79) were more likely to be in the high risk than the low risk behavior group. Moreover, middle school students who were male ( OR =2.30), had an extended family ( OR =1.18), had a reorganized family ( OR =1.70), had other family types ( OR =1.94), possibly had depressed feelings ( OR =3.10), had depressed feelings ( OR =4.91), had taken sick leave in the prior 2 weeks ( OR =1.54), or had absence from school because of illness in the past year ( OR =1.71) were relatively more likely to be in the low lack of exercise or high intentional injury group ( P <0.05).@*Conclusion@#Clear latent classes of health risk behaviors among middle school students are found to be present in differing proportions in Beijing. Relevant departments should take targeted intervention measures in a timely manner to reduce the occurrence of health risk behaviors among middle school students.
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Objective To summarize the clinical features of patients with ovarian tumor associated anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis,and to explore the influence of operation patterns on the prognosis.Methods The clinical data of ovarian tumors with anti-NMDAR encephalitis in the Third Affiliated Hospital of Sun Yat-sen University from January 2009 to December 2018 were collected,and the clinical characteristics,treatment and prognosis were analyzed.Results A total of 110 patients with ovarian tumors and anti-NMDAR encephalitis were collected.All patients were positive for anti-NMDAR antibodies in serum and/or cerebrospinal fluid.The age of onset ranged from 10 to 35 years (24.6 ±5.7).About 60.9％ patients'initial symptom was psychosis.The main clinical features were psychosis (97.3％),seizures (83.6％),conscious disturbance (72.7％),autonomic dysfunction (64.5％),dyskinesia (64.5％),central hypoventilation (54.5％) and impaired memory (31.8％).Most patients'symptoms were relieved after surgery and immunotherapy.Postoperative pathological results revealed that ovarian teratoma accounted for 97.8％ of the ovarian tumor.The prognosis of patients with surgery was better than the patients without surgery,with statistically significant difference (P ＜ 0.05).The prognosis of patients with adnexectomy was better than the patients with ovarian tumor excision,with statistically significant difference (P ＜ 0.05).Conclusions Anti-NMDAR encephalitis,with psycho-neurological symptoms as dominant manifestation,is usually associated with ovarian tumor.For young female patients with psychosis,clinicians should be alert to the possibility of anti-NMDAR encephalitis and screen for tumor.Patients with adnexectomy and immunotherapy can get a better prognosis.
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@#Objective To explore the effects of partial body weight support treadmill training (PBWSTT) combined with brain function therapy on walking ability of stroke patients. Methods 112 stroke patients with hemiplegia were randomly allocated into treatment group (n=57) and control group (n=55). The control group received routine rehabilitation training, while the treatment group received PBWSTT combined with brain function therapy in addition. They were assessed with lower limb's movement and balance function assessment of the Fugl-Meyer Assessment (FMA), Functional Ambulation Category (FAC), and Modified Barthel Index (MBI) before and after the treatment. Results The scores of FMA, FAC, and MBI improved more in treatment group than in control group after treatment (P<0.05). Conclusion Based on the conventional rehabilitation, PBWSTT combined with brain function therapy may improve the motor function of lower limb, balance function，walking ability, and ADL more significantly in stroke patients with hemiplegia.
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@#Objective To observe the effect of Zhenganxifeng decoction and Buyanghuanwu decoction on the early rehabilitation of the stroke.Methods 101 cases with acute stroke were randomly divided into the treatment group(n=51) and control group(n=50).All patients were treated with routine medical therapy,physiotherapy and electric stimulation for a month.The treatment group was treated with Zhenganxifeng decoction while the control group with Buyanghuanwu decoction in addition.Results The motor function and Activities of Daily Living(ADL) in both groups were improved after treatment,but were better in treatment group than in control group(P<0.01).Conclusion It is better to use Zhenganxifeng decoction in the early rehabilitation of the stroke than Buyanghuanwu decoction.
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Objective To investigate the role of follicle stimulating hormone receptor (FSHR) expression on granulosa cells in ovarian response of women undergoing gonadotropin stimulation. Methods A total of 60 women were recruited and divided into poor, moderate and high responders according to the number of follicles. FSHR expression was detemined by Western blot on granulosa cells obtained by follicular aspiration. The peak levels of serum estradiol (E_2) were meassured by immunofluorescent assay. Results (1) The expression of FSHR was significantly different among the 3 groups, being 0.19?0.07, 0.34?0.16, and 0.45?0.18 for poor, moderate and high responders, respectively(P
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Objective To investigate whether the limited ovarian stimulation (LOS) could avoid the severe ovarian hyperstimulation syndrome (OHSS) in patients with high risk of OHSS. Methods Ten infertile patients were diagnosed as polycystic ovarian syndrome(PCOS) with high risk of OHSS. All of them were arranged LOS cycles, a long-induction protocol using gonadotropin releasing hormone agonist (GnRHa) for controlled ovarian hyperstimulation. A full dose of human chorionic gonadotropin (10 000 U) was administered when the leading follicle reached a mean diameter of 12.0-14.5 mm. Oocytes were retrieved 36 hours later, followed by conventional in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) and embryo transfer. Results Ten patients produced 11-35 oocytes, including 4-28 oocytes of metaphase Ⅱ. Embryos were transferred in all of ten patients and eight clinical pregnancies were diagnosed. Unfortunately, ectopic pregnancy occurred in one of the patients. None of them experienced the symptoms of OHSS. Conclusions LOS may play a valuable role in preventing OHSS and achieving enough mature oocytes for the patients of PCOS. Furthermore, this protocol would not reduce the pregnancy rate of the patients.